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. 2015 Nov 13;7(1):610–621. doi: 10.18632/oncotarget.6311

Figure 6. Combination of compound 968 and erlotinib inhibits the glutamine and glycolysis metabolism.

Figure 6

The concentrations of Glutamine (A), glutamate (B), glucose (C), lactate (D), and ATP (E) were detected in HCC827, HCC827ER cells or HCC827ER cells treated with compound 968 (10 μM) combined with erlotinib (1 μM). Data represent the average of three independent experiments (mean ± SD). *P < 0.05, **P < 0.01, ***P < 0.001. (F) A summary map of metabolites from glycolysis and glutamine metabolism in this study.