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. 2015 Nov 27;7(1):845–859. doi: 10.18632/oncotarget.6417

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Copyright: © 2016 Airiau et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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HL-60, THP-1 or U-937 cells were analyzed by western blot for expression of the Bcl-2 family proteins. The three cell lines were treated for 24 h with 1 μM MEKI, 200 nM ABT-263 or both (Mix) and analyzed for Erk1/2 phosphorylation, BIM, Bcl-2, BAX, Bcl-XL, Mcl-1 and PUMA expression and Caspase 3 cleavage.