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. 2015 Oct 15;7(1):961–975. doi: 10.18632/oncotarget.5830

Figure 7. The involvement of BMP and autophagy pathway induced by linc-POU3F3 knockdown.

Figure 7

A–B. The protein expressions of BMP pathway (BMPR1, BMPR2, SMAD4, and pSMAD1, 5, 8) and autophagy pathway (Atg5, Atg7, Beclin 1, and LC3) induced by linc-POU3F3 knockdown in LOVO, SW480, and RKO cells were determined by Western blotting. C–D. The protein levels of BMP pathway and autophagy pathway in LOVO, SW480, and RKO cells were showed in these panels. - E. TEM showing the formation of autophagosomes after siRNA treatment in LOVO and SW480 cells. Representative images of autophagosomes are shown at the bottom (white arrowheads). The images were taken at × 5000. (Mean ± SD, n = 3; *P < 0.05 vs. NC).