Table 1. Univariate analysis of the impact of metastatic lymph node variables on survival.
| A. Survival impact of N stages in all distant metastatic gastric cancer (DMGC) patients, DMGC patients without nodal dissection alone, and DMGC patients with nodal dissection alone. | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Cohortsof all patients | All patients | Without LND | With LND | ||||||
| MS (m) | 3-YSR (%) | P | MS (m) | 3-YSR (%) | P | MS (m) | 3-YSR (%) | P | |
| N stage | |||||||||
| N0 | 13.0 | 25.5 | Ref. | 9.0 | 13.0 | Ref. | 18.0 | 35.1 | Ref. |
| N1–N3 | 10.0 | 14.2 | 0.000 | 7.0 | 5.1 | 0.206 | 11.0 | 14.6 | 0.000 |
| N1 | 12.0 | 17.8 | 0.000 | 7.0 | 5.1 | 0.206 | 12.0 | 19.4 | 0.000 |
| N2 | 9.0 | 10.6 | 0.036 | NA | NA | NA | 9.0 | 10.7 | 0.000 |
| N3 | 10.0 | 11.2 | 0.011 | NA | NA | NA | 10.0 | 11.2 | 0.000 |
| Abbreviations: LND, lymph node dissection; MS, median survival; m, months; YSR, year survival rate; Ref, reference; NA, not applicable. | |||||||||
| B. Survival impact of lymph node ratio in all DMGC patients with nodal dissection, patients with positive nodes, and patients of same N stages. | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patients with LND | All patients | N1–N3 | N1 | N2 | N3 | ||||||||||
| MS (m) | 3-YSR (%) | P | MS (m) | 3-YSR (%) | P | MS (m) | 3-YSR (%) | P | MS (m) | 3-YSR (%) | P | MS (m) | 3-YSR (%) | P | |
| LNR | 0.000 | ||||||||||||||
| [0–0.2] | 19.0 | 34.0 | Ref | 19.0 | 32.3 | Ref. | 19.0 | 33.5 | Ref. | NA | NA | NA | NA | NA | NA |
| (0.2–0.4] | 14.0 | 18.6 | 0.002 | 14.0 | 18.8 | 0.014 | 13.0 | 20.0 | 0.015 | 16.0 | 13.5 | Ref. | NA | NA | NA |
| (0.4–0.6] | 12.0 | 16.4 | 0.000 | 12.0 | 16.4 | 0.002 | 12.0 | 14.6 | 0.006 | 12.0 | 14.0 | 0.503 | 18.0 | 30.8 | Ref. |
| (0.6–0.8] | 11.0 | 9.4 | 0.000 | 11.0 | 9.4 | 0.000 | 11.0 | 10.6 | 0.001 | 9.0 | 10.7 | 0.101 | 11.0 | 6.0 | 0.059 |
| (0.8–1.0] | 8.0 | 8.5 | 0.000 | 8.0 | 8.5 | 0.000 | 8.0 | 6.2 | 0.000 | 7.0 | 9.1 | 0.003 | 8.0 | 9.2 | 0.009 |
| LNR | 0.000 | ||||||||||||||
| [0–0.6] | 16.0 | 24.7 | Ref. | 15.0 | 21.8 | Ref. | 15.0 | 24.3 | Ref. | 13.0 | 13.3 | Ref. | 21.0 | 32.7 | Ref. |
| (0.6–1] | 8.0 | 8.8 | 0.000 | 8.0 | 8.8 | 0.000 | 8.0 | 7.6 | 0.000 | 8.0 | 9.6 | 0.000 | 9.0 | 8.3 | 0.004 |
| Abbreviations: LND, lymph node dissection; MS, median survival; m, months; YSR, year survival rate; LNR, lymph node ratio; Ref, reference; NA, not applicable. | |||||||||||||||