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. 2015 Oct 19;7(1):1029–1041. doi: 10.18632/oncotarget.6009

Table 5. Survival impact of lymph node dissection according to multivariate analysis.

Item All patients Patients with positive nodes
All patients With LND All patients With LND
HR 95% CI HR 95% CI HR 95% CI HR 95% CI
Agea 1.005* 1.001–1.009 1.005* 1.000–1.010 NS NS
T stage (vs. T0–T2) 1.276** 1.115–1.461 NS 1.202* 1.037–1.392 NS
Grade (vs. I–II) 1.261** 1.085–1.464 1.222* 1.031–1.448 1.250* 1.053–1.483 NS
Tumor extent (vs. Localized)
Further extent 1.459** 1.155–1.843 1.616** 1.223–2.134 1.589** 1.214–2.080 1.583** 1.184–2.116
Mets at diag (vs. DNs)
OPI 1.326** 1.125–1.562 1.255** 1.052–1.496 1.198* 1.006–1.427 NS
OPI and DNs 1.433** 1.132–1.813 NS 1.405** 1.088–1.815 NS
Radi & Surgery (vs. Surgery alone) 0.724** 0.615–0.853 0.709** 0.593–0.848 0.637** 0.530–0.766 0.644** 0.531–0.781
LND (vs. Not performed 0.811* 0.680–0.967 NA 0.628** 0.456–0.864 NA
LNDa NA 0.969** 0.959–0.978 NA 0.969** 0.960–0.979
PLNa NA 1.041** 1.029–1.052 NA 1.037** 1.025–1.050

Survival impact of undergoing lymph node dissection and the number of dissections as determined by multivariate analysis in all distant metastatic gastric cancer patients, and patients with positive nodes.

a

Continuous variable

*

P < 0.05

**

P < 0.01.

Abbreviations: HR, hazard ratio; CI, confidence interval; LND, lymph node dissection; PLN, positive lymph node; NA, not applicable; NS, not significance; Mets, metastasis status; diag, diagnosis; OPI, organs or peritoneal involved; DNs, distant nodes; Radi, radiation; Surg, surgery.