Table 5. Survival impact of lymph node dissection according to multivariate analysis.
Item | All patients | Patients with positive nodes | ||||||
---|---|---|---|---|---|---|---|---|
All patients | With LND | All patients | With LND | |||||
HR | 95% CI | HR | 95% CI | HR | 95% CI | HR | 95% CI | |
Agea | 1.005* | 1.001–1.009 | 1.005* | 1.000–1.010 | NS | NS | ||
T stage (vs. T0–T2) | 1.276** | 1.115–1.461 | NS | 1.202* | 1.037–1.392 | NS | ||
Grade (vs. I–II) | 1.261** | 1.085–1.464 | 1.222* | 1.031–1.448 | 1.250* | 1.053–1.483 | NS | |
Tumor extent (vs. Localized) | ||||||||
Further extent | 1.459** | 1.155–1.843 | 1.616** | 1.223–2.134 | 1.589** | 1.214–2.080 | 1.583** | 1.184–2.116 |
Mets at diag (vs. DNs) | ||||||||
OPI | 1.326** | 1.125–1.562 | 1.255** | 1.052–1.496 | 1.198* | 1.006–1.427 | NS | |
OPI and DNs | 1.433** | 1.132–1.813 | NS | 1.405** | 1.088–1.815 | NS | ||
Radi & Surgery (vs. Surgery alone) | 0.724** | 0.615–0.853 | 0.709** | 0.593–0.848 | 0.637** | 0.530–0.766 | 0.644** | 0.531–0.781 |
LND (vs. Not performed | 0.811* | 0.680–0.967 | NA | 0.628** | 0.456–0.864 | NA | ||
LNDa | NA | 0.969** | 0.959–0.978 | NA | 0.969** | 0.960–0.979 | ||
PLNa | NA | 1.041** | 1.029–1.052 | NA | 1.037** | 1.025–1.050 |
Survival impact of undergoing lymph node dissection and the number of dissections as determined by multivariate analysis in all distant metastatic gastric cancer patients, and patients with positive nodes.
Continuous variable
P < 0.05
P < 0.01.
Abbreviations: HR, hazard ratio; CI, confidence interval; LND, lymph node dissection; PLN, positive lymph node; NA, not applicable; NS, not significance; Mets, metastasis status; diag, diagnosis; OPI, organs or peritoneal involved; DNs, distant nodes; Radi, radiation; Surg, surgery.