Table 5. strata analysis results : independents factors associated with Time to Treatment identified by multivariate analyses, for each tumor site.

	Breast cancer				Prostate cancer				Sarcoma				Lung cancer				Colorectal cancer
	univariate		multivariate		univariate		multivariate		univariate		multivariate		univariate		multivariate		univariate		multivariate
	HR [95%CI]	p [LR]	HR [95%CI]	p [LR]	HR [95%CI]	p [LR]	HR [95%CI]	p [LR]	HR[CI]	p [LR]	AHR [CI]	p [LR]	HR [95%CI]	p [LR]	AHR [95%CI]	p [LR]	HR [95%CI]	p [LR]	AHR [95%CI]	p [LR]
AGE					1 [reference]	0.21			1 [reference]	0.08			1 [reference]	0.87			1 [reference]	0.63
[19-55]	1 [reference]	0.66			0.82 [0.34-1.95]				1.01 [0.35-2.89]				0.92 [0.56-1.51]				0.94 [0.52-1.71]
[56-65]	0.87 [0.69-1.09]				0.84 [0.37-1.94				0.29 [0.09-0.92]				0.9 [0.56-1.45]				1.14 [0.63-2.07]
[66-74]	0.90 [0.7-1.15]				1.22 [0.52-2.87]				0.46 [0.19-1.08]				0.79 [0.46-1.37]				0.82 [0.45-1.49]
[75-92]	0.94 [0.74-1.21]
GENDER
Female	1 [reference]	0.45			NA	NA			1 [reference]	0.94			1 [reference]	0.31			1 [reference]	0.003	1 [reference]	<0.001
Male	0.67 [0.21-2.08]								0.97 [0.47-1.99]				0.83 [0.58-1.19]				0.54 [0.36-0.81]		0.45 [0.29-0.71]
ECOG PS
0	1.15 [0.47-2.82]	0.66			0.06 [0.02-0.2]	<0.001	0.04 [0.01-0.2]	<0.001	0.91 [0.11-7.29]	0.64			0.57 [0.26-1.25]	0.38			0.96 [0.35-2.68]	0.52
1	0.90 [0.39-2.48]				0.06 [0.02-0.21]		0.04 [0.01-0.17]		0.61 [0.08-4.74]				0.62 [0.3-1.29]				1.02 [0.36-2.9]
2	1.12 [0.39-3.24]				0.27 [0.07-1.01]		0.21 [0.04-1.17]		0.44 [0.04-4.41]				0.49 [0.22-1.08]				1.53 [0.5-4.67]
>2	1 [reference]				1 [reference]		1 [reference]		1 [reference]				1 [reference]				1 [reference]
QUINTILE EDI
1	1 [reference]	0.49			1 [reference]	0.87	1 [reference]	0.58	1 [reference]	0.67			1 [reference]	0.74	1 [reference]	0.63	1 [reference]	0.32	1 [reference]	0.93
2	0.83 [0.62-1.09]				0.9 [0.53-1.52]		0.84 [0.48-1.47]		0.72 [0.18-2.95]				0.74 [0.41-1.34]		0.74 [0.41-1.34]		1.42 [0.73-2.78]		1.29 [0.63-2.66]
3	1.02 [0.75-1.38]				1.05 [0.58-1.88]		1.01 [0.55-1.88]		0.6 [0.16-2.32]				0.75 [0.41-1.39]		0.73 [0.39-1.35]		2.13 [1.06-4.31]		1.32 [0.63-2.77]
4	0.97 [0.71-1.35]				0.86 [0.47-1.55]		0.73 [0.38-1.41]		1.51 [0.35-6.42]				0.8 [0.44-1.44]		0.76 [0.42-1.39]		1.61 [0.8-3.23]		1.08 [0.51-2.27]
5	0.89 [0.66-1.21]				1.07 [0.62-1.85]		1.11 [0.61-2.01]		0.83 [0.22-3.07]				0.96 [0.55-1.66]		0.99 [0.57-1.72]		1.5 [0.8-2.79]		1.17 [0.6-2.29]
T staging
1	1 [reference]	0.47			1 [reference]	0.042	1 [reference]	0.045	NA	NA			1 [reference]	0.13			1 [reference]	0.017	1 [reference]	0.006
2	1.0 [0.82-1.77]				1.21 [0.84-1.74]		1.34 [0.92-1.95]		NA				1.28 [0.69-2.37]				0.84 [0.21-3.41]		0.23 [0.07-0.82]
3	0.88 [0.56-1.38]				1.83 [1.17-2.85]		2 [1.25-3.21]		NA				0.68 [0.36-1.31]				1.6 [0.5-5.14]		0.3 [0.12-0.76]
4	1.48 [0.92-2.46]				5.87 [0.79-43.74]		1.15 [0.13-10.33]		NA				1.03 [0.52-2.04]				2.68 [0.81-8.85]		0.54 [0.34-0.85]
N staging		0.3
0	1 [reference]				1 [reference]	<0.001			1 [reference]	0.7			1 [reference]	0.6			1 [reference]	0.12
1	0.93 [0.76-1.15]				5.14 [2.34-11.32]				0.52 [0.1-2.81]				1.26 [0.62-2.57]				0.8 [0.5-1.26]
2	1.22 [0.85-1.77]				NA				0.55 [0.06-5.05]				0.98 [0.57-1.71]				1.39 [0.78-2.47]
3	1.65 [0.85-3.21]				NA				NA				0.77 [0.4-1.49]				NA
M status		0.34				<0.001
0	1 [reference]				1 [reference]				1 [reference]	0.29			1 [reference]	0.09	1 [reference]	0.07	1 [reference]	0.003
1	1.26 [0.8-2.0]				7.39 [4.11-14.02]				1.59 [0.7-3.64]				1.34 [0.95-1.9]		1.38 [0.97-1.96]		1.82 [1.23-2.69]