TABLE III.
Absolute changes in full-adapt normal-tissue dose metrics compared to the no-adapt simulation. Average changes are listed below along with p-values resulting from paired t-tests comparing full-adapt and no-adapt metrics. Averages for the no-adapt simulation are listed in parentheses.
| Patient changes in normal tissue doses for full-adapt treatment | ||||||
|---|---|---|---|---|---|---|
| Cord max (cGy) | Mean lung dose (cGy) | Lung V20 (% vol) | Mean esophagus dose (cGy) | Heart D66 (cGy) | Heart D33 (cGy) | |
| PT1 | 40 | −48 | −1.39 | −415 | −2 | −3 |
| PT1N | 132 | −20 | −0.61 | −111 | 1 | −1 |
| PT3L | 259 | −69 | −1.12 | −106 | −3 | −54 |
| PT3LN | −560 | −6 | −0.15 | −68 | −5 | −151 |
| PT3R | −188 | −106 | −2.01 | −128 | −9 | −128 |
| PT3RN | −77 | −117 | −2.29 | −55 | −16 | −320 |
| PT4 | −243 | −37 | 0.69 | −72 | −43 | −148 |
| PT5 | 119 | 14 | 0.27 | −2 | 0 | 0 |
| PT6 | −325 | −43 | −0.44 | −144 | −337 | −280 |
| PT8 | −656 | −162 | −2.76 | −186 | −17 | −49 |
| PT9 | −250 | −115 | −2.96 | −2 | −2 | −22 |
| PT9N | −231 | −80 | −0.7 | 66 | 1 | 12 |
| PT14 | −187 | −92 | −1.96 | −159 | −104 | −170 |
| PT14N | −91 | −37 | −0.7 | −15 | 0 | 38 |
| PT17 | −8 | −54 | 1.06 | −294 | −27 | −80 |
| PT17N | −656 | −100 | −1.72 | −253 | −14 | −54 |
| PT18 | 65 | 8 | 0 | 26 | 15 | 69 |
| PT20 | 311 | 10 | 0.05 | 1 | −7 | −7 |
| PT20N | −363 | −64 | −2.43 | −231 | −39 | −104 |
| PT21 | 104 | −106 | −2.22 | −47 | −87 | −367 |
| Mean change | −158 | −65 | −1.1 | −117 | −37 | −99 |
| (Mean no-adapt) | (4202) | (1350) | (23) | (2106) | (504) | (1174) |
| p | 0.04 | 0.000 01 | 0.0006 | 0.0005 | 0.05 | 0.002 |