Table 1.
Parameter | Standard approach | Iterative approach |
---|---|---|
R K [nmol] | 1.4a | 2.1 ± 0.8b |
R L [nmol] | 2.1a | 1.8 ± 0.7b |
R S [nmol] | 3.8a | 3.5 ± 3.1b |
R R [nmol] | 6.4a | 7.3 ± 2.5b |
V T [l] | 0.3a | 0.2 ± 0.3b |
f T [ml/min/g] | 0.2 ± 0.1b | 0.25 ± 0.06b |
f ex [%] | 96 ± 1.0b | 96c |
GFR [ml/min] | 57.4a | 64.4 ± 15.1b |
λ deg,T [10−4/min] | 1.1a | 1.5 ± 0.6b |
λ deg,K [10−4/min] | 1.1 ± 0.1b | 1.1c |
λ deg,L [10−4/min] | 0.5 ± 0.1b | 0.5c |
λ deg,S [10−4/min] | 1.6 ± 0.1b | 1.6c |
λ deg,R [10−4/min] | 1.3 ± 0.1b | 1.3c |
# of fitting parameters | 13 | 8 |
aAdjustable parameters
bBayes parameters with mean ± SD
cFixed parameter values