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. 2016 Mar 25;6:30. doi: 10.1186/s13550-016-0185-8

Table 1.

Model parameters and start values of the fitting parameters

Parameter Standard approach Iterative approach
R K [nmol] 1.4a 2.1 ± 0.8b
R L [nmol] 2.1a 1.8 ± 0.7b
R S [nmol] 3.8a 3.5 ± 3.1b
R R [nmol] 6.4a 7.3 ± 2.5b
V T [l] 0.3a 0.2 ± 0.3b
f T [ml/min/g] 0.2 ± 0.1b 0.25 ± 0.06b
f ex [%] 96 ± 1.0b 96c
GFR [ml/min] 57.4a 64.4 ± 15.1b
λ deg,T [10−4/min] 1.1a 1.5 ± 0.6b
λ deg,K [10−4/min] 1.1 ± 0.1b 1.1c
λ deg,L [10−4/min] 0.5 ± 0.1b 0.5c
λ deg,S [10−4/min] 1.6 ± 0.1b 1.6c
λ deg,R [10−4/min] 1.3 ± 0.1b 1.3c
# of fitting parameters 13 8

aAdjustable parameters

bBayes parameters with mean ± SD

cFixed parameter values