Table 3.
Mean relative deviations of the fitted and reference TIACs averaged over all patients and all organs. For cases I to IV, the combination of omitted measurement points that gave the best and worst results in terms of the lowest and largest relative deviation (above and below the dashed line) are presented
| RD [%] | Standard approach | Iterative approach | ||||||
|---|---|---|---|---|---|---|---|---|
| Case | Omitted time point | Mean ± SD | Min | Max | Omitted time point | Mean ± SD | Min | Max |
| 0 | – | (Reference) | – | 1 ± 5 | −6 | 13 | ||
| I | 2nd | 0 ± 4 | −6 | 9 | 4th | 2 ± 6 | −10 | 13 |
| 4th | −1 ± 6 | −16 | 9 | 3rd | 0 ± 11 | −19 | 26 | |
| II | 2nd, 4th | 0 ± 6 | −11 | 13 | 1st, 3rd | 0 ± 7 | −14 | 15 |
| 3rd, 5th | 6 ± 39 | −36 | 133 | 3rd, 5th | 1 ± 11 | −13 | 31 | |
| III | 1st, 3rd, 5th | 5 ± 17 | −13 | 51 | 1st, 3rd, 5th | 0 ± 8 | −12 | 18 |
| 2nd, 3rd, 5th | 22 ± 58 | −26 | 175 | 3rd, 4th, 5th | 22 ± 86 | −34 | 309 | |
| IV | –a | 1st, 2nd, 4th, 5th | 6 ± 13 | −15 | 37 | |||
| –a | 1st, 3rd, 4th, 5th | 16 ± 55 | −26 | 188 | ||||
| V | 1st–8thb | 0 ± 3 | −7 | 9 | 1st–8thb | 1 ± 5 | −6 | 14 |
aNo fitting was performed for the standard approach, because an equal number of data and fitting parameters were present
bOnly serum measurements omitted