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. 2016 Mar 25;60(4):2185–2194. doi: 10.1128/AAC.02659-15

TABLE 1.

Susceptibility of biofilm-associated C. albicans cells from clinical isolates to antimicrobials

Antimicrobial 50% RMA (μg/ml)a 50% RS (μg/ml)b
Voriconazole 64 32
Fluconazole 64 64
NO-np 5,000 (5.64 × 10−6c; 3.76 × 10−6d,e) 5,000 (5.64 × 10−6c; 3.76 × 10−6d,e)
a

50% RMA, a 50% reduction in metabolic activity, as determined by the XTT reduction assay.

b

50% RS, a 50% reduction in survival, as determined by the CFU killing assay.

c

Actual nitric oxide in solution for initial peak.

d

Actual nitric oxide in solution for steady state.

e

P < 0.05.

HHS Vulnerability Disclosure