TABLE 1.
Susceptibility of biofilm-associated C. albicans cells from clinical isolates to antimicrobials
Antimicrobial | 50% RMA (μg/ml)a | 50% RS (μg/ml)b |
---|---|---|
Voriconazole | 64 | 32 |
Fluconazole | 64 | 64 |
NO-np | 5,000 (5.64 × 10−6c; 3.76 × 10−6d,e) | 5,000 (5.64 × 10−6c; 3.76 × 10−6d,e) |
50% RMA, a 50% reduction in metabolic activity, as determined by the XTT reduction assay.
50% RS, a 50% reduction in survival, as determined by the CFU killing assay.
Actual nitric oxide in solution for initial peak.
Actual nitric oxide in solution for steady state.
P < 0.05.