FIG 1.

Parthenin treatment of gametocytemic blood concurrent to blood feeding results in lower oocyst counts. (A) Replicate 2 showing statistically significant decreases in oocyst counts (denoted by asterisks and determined using zero-inflated GLMM analysis and a P value of <0.05). P values were <0.0001 for 100, 50, 25, and 12.5 μg/ml and above the 0.05 cutoff for 6.25 μg/ml. (B) Table summarizing the sample size, median oocyst number, percent inhibition in median oocyst numbers, and prevalence of infection for all three replicates (replicates 1 and 3 are shown in Fig. S3 in the supplemental material).