TABLE 1.
Baseline characteristics of the 190 neonates
| Characteristic | Mean (SD) | Median (range) |
|---|---|---|
| Gestational age (wks) | 31.1 (4.9) | 30 (24–42) |
| Birth wt (g) | 1,563.0 (844.0) | 1,290 (512–4,180) |
| Current wt (at time of dosing) (g) | 1,755.0 (872.5) | 1,525 (540–4,750) |
| Postnatal age (days) | 16.7 (21.7) | 10 (0–196) |
| Baseline serum creatinine concna (μmol/liter) | 48.6 (21.8) | 46 (14.0–125.0) |
| Vancomycin loading dose (mg/kg/day) | 11.1 (0.6) | 11.1 (9.9–12.6) |
| Vancomycin maintenance dose (mg/kg/day) | 28.3 (9.9) | 25.4 (13.0–61.0) |
a
Within 48 h before inclusion.