Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
In vitro activities (EC50s) and SIs of the tested compounds against intracellular forms of Trypanosoma cruzi Y in CCs at 48 h after incubation at 37°C
| Compound | EC50 (μM) | EC90 (μM) | SIa |
|---|---|---|---|
| 35DAP073 | 0.016 ± 0.007b | 0.087 ± 0.009b | 2,000 |
| 35DAP081 | 0.23 ± 0.06b | 0.9 ± 0.05b | 139 |
| Benznidazole | 3.6 ± 1.7 | 11 ± 2.7 | 277 |
The SI data are related to the EC50 values.
P < 0.05 by ANOVA.
