Table 1.
Baseline characteristics of patients with ESRD on dialysis undergoing PCI with stenting in the overall cohort, and after propensity score-matching and applying the inverse probability of treatment weighting.
| Full Cohort | Propensity Score-Matched | Inverse Probability of Treatment Weighted | |||||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| BMS | DES | Std Diff | BMS | DES | Std Diff | BMS | DES | Std Diff | |
|
| |||||||||
| N | 11202 | 24915 | 10751 | 10751 | 11202 | 24915 | |||
|
| |||||||||
| Demographics | |||||||||
| Age, mean (SD), years | 64.6 (12.1) | 64.0 (11.8) | 5.0 | 64.6 (12.1) | 64.5 (11.7) | 0.8 | 64.2 (11.9) | 64.2 (11.8) | 0.0 |
| Male | 58.3 | 55.3 | 6.1 | 58.1 | 58.0 | 0.3 | 56.5 | 56.2 | 0.6 |
| Race | |||||||||
| White | 64.2 | 64.2 | 0.02 | 64.3 | 64.8 | 1.1 | 65.1 | 64.4 | 1.5 |
| Black | 30.5 | 29.4 | 2.5 | 30.4 | 30.0 | 1.0 | 28.9 | 29.6 | 1.5 |
| Asian | 3.2 | 4.1 | 5.0 | 3.2 | 3.3 | 0.5 | 3.8 | 3.8 | 0.2 |
| Other/Unknown | 2.1 | 2.3 | 1.5 | 2.1 | 1.9 | 1.1 | 2.2 | 2.2 | 0.1 |
|
| |||||||||
| Peritoneal Dialysis | 7.2 | 7.2 | 0.2 | 7.1 | 7.1 | 0.0 | 7.0 | 7.2 | 0.6 |
|
| |||||||||
| Vintage, median (IQR), years | 3.1 (1.6–5.3) | 2.7 (1.4–4.8) | 10.0 | 3.0 (1.5–5.3) | 2.9 (1.5–5.2) | 0.0 | 2.9 (1.5–5.0) | 2.8 (1.4–5.0) | 0.0 |
|
| |||||||||
| Cause of end-stage renal disease | |||||||||
| Diabetes | 52.4 | 59.8 | 15.0 | 53.1 | 54.0 | 1.8 | 57.7 | 57.5 | 0.5 |
| Hypertension | 27.8 | 23.9 | 9.0 | 27.5 | 27.3 | 0.5 | 25.1 | 25.1 | 0.1 |
| Glomerulonephritis | 8.4 | 6.5 | 7.3 | 8.1 | 7.9 | 0.6 | 7.0 | 7.1 | 0.4 |
| Other/Unknown | 11.4 | 9.8 | 5.2 | 11.3 | 10.8 | 1.6 | 10.2 | 10.3 | 0.2 |
|
| |||||||||
| Non-nephrology outpatient visits, 6M prior, median (IQR) | 20 (12–31) | 21 (13–31) | 2.8 | 20 (12–31) | 20 (12–31) | 1.1 | 20 (12–31) | 20 (12–31) | 0.0 |
|
| |||||||||
| Hospital days in 6m prior, median (IQR) | 3 (1–10) | 3 (1–9) | 4.0 | 3 (1–10) | 3 (1–10) | 0.0 | 3 (1–10) | 3 (1–10) | 0.0 |
|
| |||||||||
| Any nursing home stay | 7.7 | 7.3 | 1.4 | 7.8 | 7.7 | 0.5 | 7.1 | 7.4 | 1.0 |
|
| |||||||||
| On kidney transplant waiting list | 15.3 | 15.1 | 0.5 | 15.2 | 14.9 | 0.9 | 15.2 | 15.2 | 0.1 |
|
| |||||||||
| Multivessel intervention | 13.2 | 17.4 | 11.6 | 13.6 | 13.7 | 0.2 | 15.8 | 16.1 | 0.6 |
|
| |||||||||
| Index Presentation | |||||||||
|
| |||||||||
| Stable coronary artery disease | 58.7 | 64.7 | 12.3 | 59.4 | 59.6 | 0.4 | 62.8 | 62.9 | 0.2 |
| ST-elevation MI | 10.7 | 5.9 | 17.2 | 9.7 | 8.7 | 3.2 | 7.4 | 7.4 | 0.2 |
| Non-ST elevation MI | 30.2 | 28.9 | 2.9 | 30.5 | 31.3 | 1.7 | 29.3 | 29.3 | 0.1 |
| Unstable angina | 0.4 | 0.5 | 1.0 | 0.4 | 0.4 | 0.4 | 0.5 | 0.5 | 0.1 |
|
| |||||||||
| Cardiovascular Comorbidities | |||||||||
|
| |||||||||
| CABG prior to index | 26.2 | 24.0 | 5.1 | 26.1 | 26.2 | 0.3 | 25.2 | 24.7 | 1.0 |
|
| |||||||||
| PCI prior to index | 13.2 | 15.8 | 7.2 | 13.4 | 13.9 | 1.3 | 15.5 | 15.0 | 1.3 |
|
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| Myocardial infarction | 53.6 | 48.4 | 10.3 | 52.9 | 53.3 | 0.7 | 50.1 | 50.0 | 0.3 |
|
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| Angina | 56.1 | 59.8 | 7.5 | 56.3 | 56.6 | 0.5 | 58.9 | 58.6 | 0.6 |
|
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| Heart failure | 78.5 | 78.5 | 0.1 | 78.6 | 79.0 | 1.0 | 78.9 | 78.5 | 0.8 |
|
| |||||||||
| Hypertension | 99.9 | 99.8 | 2.5 | 99.9 | 99.8 | 1.2 | 99.8 | 99.8 | 0.6 |
|
| |||||||||
| Atrial fibrillation | 30.2 | 27.1 | 7.0 | 30.1 | 29.8 | 0.7 | 27.9 | 28.0 | 0.1 |
|
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| Other arrhythmia | 34.1 | 30.8 | 7.0 | 34.0 | 33.8 | 0.3 | 31.7 | 31.8 | 0.2 |
|
| |||||||||
| Stroke/Transient Ischemic Attack | 25.3 | 24.5 | 1.9 | 25.4 | 26.4 | 2.1 | 25.0 | 24.7 | 0.7 |
|
| |||||||||
| Valvular disease | 45.8 | 42.4 | 6.8 | 45.8 | 45.4 | 0.7 | 43.9 | 43.5 | 0.9 |
|
| |||||||||
| Peripheral arterial disease | 56.4 | 55.9 | 0.9 | 56.6 | 56.8 | 0.4 | 56.2 | 56.1 | 0.3 |
|
| |||||||||
| Cerebrovascular disease | 25.9 | 25.7 | 0.4 | 26.1 | 26.6 | 1.1 | 25.8 | 25.8 | 0.1 |
|
| |||||||||
| Other comorbid conditions | |||||||||
|
| |||||||||
| Diabetes mellitus | 77.2 | 81.9 | 11.6 | 77.9 | 79.2 | 3.2 | 80.6 | 80.4 | 0.4 |
|
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| Hyperlipidemia | 72.6 | 74.2 | 3.7 | 73.2 | 74.3 | 2.4 | 73.9 | 73.7 | 0.4 |
|
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| Gastrointestinal bleeding | 31.1 | 27.7 | 7.6 | 30.8 | 30.5 | 0.6 | 28.9 | 28.7 | 0.3 |
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| Peptic ulcer disease | 8.8 | 7.6 | 4.3 | 8.6 | 8.7 | 0.2 | 7.9 | 7.9 | 0.1 |
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| Intracranial hemorrhage | 2.8 | 2.0 | 4.9 | 2.7 | 2.8 | 0.7 | 2.3 | 2.3 | 0.1 |
|
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| Liver disease | 17.3 | 15.6 | 4.5 | 17.2 | 17.2 | 0.0 | 16.2 | 16.1 | 0.1 |
|
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| Chronic lung disease | 47.3 | 45.1 | 4.5 | 47.4 | 48.0 | 1.3 | 46.3 | 45.8 | 1.0 |
|
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| Smoking history | 17.9 | 14.8 | 8.2 | 17.7 | 17.5 | 0.3 | 15.9 | 15.8 | 0.3 |
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| Dementia | 7.5 | 7.0 | 1.9 | 7.6 | 7.7 | 0.6 | 6.9 | 7.1 | 0.8 |
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| Depression | 23.3 | 22.7 | 1.5 | 23.3 | 24.4 | 2.4 | 22.7 | 22.9 | 0.3 |
|
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| Cancer | 15.1 | 12.9 | 6.3 | 14.9 | 14.6 | 0.9 | 13.6 | 13.6 | 0.01 |
|
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| Hypothyroid | 19.1 | 19.1 | 0.1 | 19.1 | 19.4 | 0.8 | 18.9 | 19.1 | 0.5 |
|
| |||||||||
| Obesity | 17.2 | 17.8 | 1.7 | 17.4 | 18.1 | 1.8 | 17.8 | 17.6 | 0.3 |
All values are % unless otherwise noted. Abbreviations: BMS = bare metal stent; DES = drug eluting stent; Std Diff – standardized differences; SD = standard deviation; IQR = interquartile range; MI = myocardial infarction; PCI = percutaneous coronary intervention; CABG = coronary artery bypass grafting;