Table 2.
Baseline characteristics of patients with end-stage renal disease on dialysis undergoing percutaneous coronary intervention with stenting, stratified by drug-eluting stent era.
| Transitional 4/23/03–6/30/04 | Liberal 7/1/04–12/31/06 | Selective 1/1/07–12/31/10 | Std Diff Transition al vs Liberal | Std Diff Selective vs Liberal | |
|---|---|---|---|---|---|
|
| |||||
| N | 5372 | 12349 | 18396 | – | – |
|
| |||||
| Demographics | |||||
| Age, mean (SD), years | 63.8 (12.0) | 64.2 (11.9) | 64.2 (11.8) | 3.7 | 0.5 |
| Male | 55.1 | 56.0 | 56.7 | 1.8 | 1.4 |
| Race | |||||
| White | 64.3 | 63.4 | 64.8 | 1.8 | 2.8 |
| Black | 30.1 | 30.5 | 29.1 | 0.9 | 3.1 |
| Asian | 3.6 | 3.6 | 4.0 | 0.2 | 2.2 |
| Other/Unknown | 2.0 | 2.5 | 2.1 | 2.8 | 2.3 |
|
| |||||
| Peritoneal Dialysis | 7.8 | 7.1 | 7.1 | 2.8 | 0.1 |
|
| |||||
| Vintage, median (IQR), years | 2.7 (1.4–4.9) | 2.7 (1.4–4.8) | 2.9 (1.5–5.1) | 1.5 | 6.3 |
|
| |||||
| Cause of end-stage renal disease | |||||
| Diabetes | 56.4 | 57.6 | 57.8 | 2.5 | 0.2 |
| Hypertension | 25.6 | 24.8 | 25.2 | 1.8 | 1.0 |
| Glomerulonephritis | 8.3 | 7.2 | 6.6 | 4.1 | 2.3 |
| Other/Unknown | 9.7 | 10.4 | 10.4 | 2.1 | 0.0 |
|
| |||||
| Non-nephrology outpatient visits, 6M prior, median (IQR) | 20 (12–29) | 20 (12–31) | 21 (13–32) | 6.4 | 8.0 |
|
| |||||
| Hospital days in 6m prior, median (IQR) | 3 (1–10) | 3 (1–10) | 3 (1–10) | 0.1 | 0.0 |
|
| |||||
| Any nursing home stay | 5.7 | 7.1 | 8.2 | 5.8 | 4.3 |
|
| |||||
| On kidney transplant waiting list | 14.3 | 15.0 | 15.5 | 1.9 | 1.5 |
|
| |||||
| Multivessel intervention | 9.2 | 16.0 | 18.2 | 20.4 | 5.9 |
|
| |||||
| Index Presentation | |||||
|
| |||||
| Stable coronary artery disease | 67.3 | 66.8 | 58.9 | 0.9 | 16.5 |
| ST-elevation myocardial infarction | 8.2 | 6.9 | 7.6 | 4.9 | 2.7 |
| Non-ST elevation myocardial infarction | 24.1 | 25.8 | 33.1 | 4.0 | 16.2 |
| Unstable angina | 0.5 | 0.5 | 0.4 | 0.2 | 1.7 |
|
| |||||
| Cardiovascular Comorbidities | |||||
|
| |||||
| Coronary artery bypass grafting prior to index | 24.6 | 24.9 | 24.6 | 0.7 | 0.6 |
|
| |||||
| Percutaneous coronary intervention prior to index | 12.9 | 13.9 | 16.3 | 3.0 | 6.5 |
|
| |||||
| Myocardial infarction | 46.6 | 46.4 | 53.4 | 0.5 | 14.2 |
|
| |||||
| Angina | 60.9 | 60.6 | 56.7 | 0.6 | 7.9 |
|
| |||||
| Heart failure | 76.0 | 77.9 | 79.6 | 4.4 | 4.2 |
|
| |||||
| Hypertension | 99.5 | 99.8 | 99.9 | 4.4 | 2.6 |
|
| |||||
| Atrial fibrillation | 26.8 | 27.7 | 28.6 | 2.1 | 2.0 |
|
| |||||
| Other arrhythmia | 29.1 | 30.8 | 33.3 | 3.7 | 5.5 |
|
| |||||
| Stroke/Transient ischemic attack | 22.5 | 23.1 | 26.5 | 1.3 | 7.9 |
|
| |||||
| Valvular disease | 40.7 | 43.5 | 44.2 | 5.8 | 1.3 |
|
| |||||
| Peripheral arterial disease | 53.7 | 55.4 | 57.2 | 3.3 | 3.8 |
|
| |||||
| Cerebrovascular disease | 23.7 | 24.3 | 27.4 | 1.5 | 7.1 |
|
| |||||
| Other comorbid conditions | |||||
|
| |||||
| Diabetes mellitus | 76.9 | 79.1 | 82.4 | 5.4 | 8.4 |
|
| |||||
| Hyperlipidemia | 61.8 | 69.5 | 80.0 | 16.2 | 24.5 |
|
| |||||
| Gastrointestinal bleeding | 27.6 | 28.7 | 29.1 | 2.3 | 1.0 |
|
| |||||
| Peptic ulcer disease | 8.3 | 8.1 | 7.7 | 0.6 | 1.6 |
|
| |||||
| Intracranial hemorrhage | 1.7 | 1.9 | 2.7 | 1.1 | 5.7 |
|
| |||||
| Liver disease | 14.4 | 15.9 | 16.8 | 4.0 | 2.7 |
|
| |||||
| Chronic lung disease | 40.8 | 44.6 | 48.0 | 7.7 | 6.7 |
|
| |||||
| Smoking history | 13.6 | 15.1 | 16.9 | 4.3 | 4.9 |
|
| |||||
| Dementia | 5.2 | 6.6 | 8.0 | 5.8 | 5.5 |
|
| |||||
| Depression | 19.5 | 21.5 | 24.7 | 4.9 | 7.7 |
|
| |||||
| Cancer | 12.1 | 13.1 | 14.4 | 3.0 | 3.8 |
|
| |||||
| Hypothyroid | 17.1 | 18.1 | 20.3 | 2.6 | 5.4 |
|
| |||||
| Obesity | 12.7 | 15.6 | 20.4 | 8.3 | 12.4 |
All values are % unless otherwise noted. Abbreviations: SD = standard deviation; IQR = interquartile range;