Differential effects of walnut supplementation on HFD-induced body weight and hepatic injury. The changes in (A) body weight, (B) food intake, (C) food efficiency ratio (FER), (D) representative liver histology with H&E staining (top panels) and oil red-O staining (bottom panels), as indicated, (E) concentration of hepatic triglyceride, (F) serum ALT, (G) hepatic steatosis score, (H) ballooning score, (I) inflammation score, and (J) NASH score in the liver tissues of experimental mice are shown. All results are presented as mean ± SEM (n=6/group). Significance was determined by one-way ANOVA with the Bonferroni correction (P<0.05). Labeled characters without a common letter represent significant differences from the other group(s). #) FER (food efficiency ratio) = Body weight gain (g)/Food intake (g) for the experimental period.