Table 2.
Results of the Age-Adjusted Cox Regression of the Effect of Statins on Cataract Progression: Hazard Ratios and 95% Confidence Limits using Unmatched Statin-Use Propensity Scores.
| N | HR | 95% CI | |
|---|---|---|---|
|
| |||
| Cataract surgery incidence | |||
| All participants | 2771 | 1.90 | 1.17–3.10 |
|
| |||
| Stratified by sex: | |||
| Females | 1540 | 2.46 | 1.25–4.85 |
| Males | 1231 | 1.48 | 0.74–2.93 |
|
| |||
| Stratified by age group: | |||
| Age < 75 years | 1824 | 2.52 | 1.20–5.33 |
| Age ≥ 75 years | 947 | 1.41 | 0.74–2.68 |
|
| |||
| Progression of cortical lens opacity | |||
| All participants | 2609 | 1.52 | 1.08–2.12 |
|
| |||
| Stratified by sex: | |||
| Females | 1438 | 1.67 | 1.03–2.71 |
| Males | 1171 | 1.40 | 0.89–2.20 |
|
| |||
| Stratified by age group: | |||
| Age < 75 years | 1738 | 1.49 | 0.94–2.36 |
| Age ≥ 75 years | 871 | 1.57 | 0.96–2.58 |
|
| |||
| Progression of posterior subcapsular lens opacity | |||
| All participants | 2673 | 1.84 | 1.25–2.71 |
|
| |||
| Stratified by sex: | |||
| Females | 1480 | 2.27 | 1.31–3.94 |
| Males | 1193 | 1.51 | 0.89–2.58 |
|
| |||
| Stratified by age group: | |||
| Age < 75 years | 1768 | 2.11 | 1.22–3.65 |
| Age ≥ 75 years | 905 | 1.54 | 0.88–2.68 |
HR = hazard ratio; CI = confidence interval. Boldface hazard ratios and confidence intervals are significant (P < 0.05). Analyses of all participants are age and sexadjusted. The analyses stratified by sex are adjusted for age, and the analyses stratified by age are adjusted for age and sex.