Illustration of differences in collagen content and alignment in histologic sections cut parallel to the epicardial surface at approximately 50% transmural depth in different experimental models and imaged under polarized light (Unpublished images of scars from studies by Fomovsky, (Fomovsky and Holmes, 2010) Holmes, (Holmes et al., 1997) and Clarke (Clarke et al., 2015)). A Rat, 3 weeks after ligation of the LAD. B Dog, 8 weeks after ligation of the left anterior descending (LAD) coronary artery. C Pig, 3 weeks after ligation of a branch of the left circumflex (LCx) coronary artery.