Figure 5.

Contrasting subcellular patterns of systolic and diastolic Ca²⁺ elevations in LQTS. A: Superimposed CaT tracings from 2 pixels of in the same myocyte. The SSCE occurs nearly simultaneously, and there is a low level of spatial heterogeneity of Ca²⁺ signal. B: In contrast, a wave of diastolic Ca²⁺ elevation propagates from top right to bottom left of the images, and can be easily seen in the left and middle image. Adapted from⁴²