Fig. 4.

The disarray of elastin and collagen was subjectively graded in a blinded manner from level 1 as the best to level 10 as the most severe disarray, as shown in Table 1. (A) The elastin disarray was greater in abdominal aorta vs. thoracic aorta for both old and young monkeys and was greater in old monkeys vs. young monkeys for both the thoracic and abdominal aorta. (B) The collagen disarray was also greater in old vs. young monkeys. Examples of elastin and collagen disarray levels of 1, 5 and 10 are shown in (C). *p<0.05 by Mann-Whitney U-Test and Kruskal–Wallis test.