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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Prog Biophys Mol Biol. 2015 Dec 25;120(1-3):270–280. doi: 10.1016/j.pbiomolbio.2015.12.012

Figure 2.

Figure 2

CA-ALT (column 1), APV-ALT (column 2), [Ca]Troponin (column 3), and FORCE-ALT (column 4) for simulations incorporating electrical remodeling in the absence of mechanical remodeling for a pacing CL of 650 ms and for SL=2.1 μm. Alternans are plotted over time in row 1 showing that CA-ALT was sufficient to produce APV-ALT, [Ca]Troponin alternans, and FORCE-ALT. Odd (blue) and even (red) beats from row 1 are superimposed to illustrate that the magnitude of alternans in rows 2 (strongly coupled simulations) and 3 (weakly coupled simulations) were different with and without myofilament feedback.