Table 3.

Results of multivariable model investigating the relationship between predictive factors and the rate of global rim area loss^*

Predictive Factor	Estimate	95% Confidence Interval	P value
Race	70.6	−46.5 to 187.7	0.237
Baseline age	3.1	−0.9 to 5.2	0.005
Central corneal thickness	1.3	0.6 to 2.0	0.001
IOP as a time dependent covariate	−-4.3	−7.6 to −1.0	0.011
Disc area	382.5	323.1 to 442	<.001
Baseline VF mean deviation	30.4	20.1 to 40.6	<.001
Standard deviation of the topography image as a time dependent covariate	−0.7	−1.3 to 0.0	0.040
Time	0.0	−5.6 to 1.9	0.996
IOP X IOP interaction term	0.1	−0.0 to 0.1	0.169
Race X time interaction term	2.2	−5.2 to 9.6	0.557
Race X group interaction term	−23.7	−89.9 to 42.5	0.482
Group X time interaction term	−2.8	−5.3 to −0.3	0.029
Race X time X group interaction term	−1.7	−8.4 to 5.0	0.623

^*- Results are presented as X10⁻³ mm²/year

- Abbreviations: IOP, Intra Ocular Pressure

- Group: Progressing glaucoma vs healthy group