Table 4.
Multivariable Rates of Global and Sectoral Rim Area Loss by group and Race
| Healthy | Progressing glaucoma | TOTAL | Stable glaucoma |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| African Descent (n=169) |
European Descent (n=127) |
Difference | African Descent (n=25) |
European Descent (n=48) |
Difference | Healthy (n=296) |
Progressing glaucoma (n=73) |
Difference | n=63 | ||
|
HRT Sector |
Mean (95% CI) P-value |
Mean (95% CI) P-value |
P value | Mean (95% CI) P-value |
Mean (95% CI) P-value |
P value | Mean (95% CI) P-value |
Mean (95% CI) P-value |
P value | Mean (95% CI) P-value |
|
|
Rim Area change X10−3 (mm2/year) |
Global |
−2.1 (−4.2, −0.02) 0.048 |
−2.3 (−4.9, 0.3) 0.081 |
0.918 |
−12.1 (−18.3, −5.8) <.001 |
−9.1 (−15.7, −2.5) 0.019 |
0.452 | −2.8 (−6.3, 0.7) 0.125 |
−10.2 (−13.9, −6.4) <.001 |
<.001 | −0.25 (−2.7, 4.0) 0.410 |
| Superior | −0.3 (−0.6, 0.1) 0.184 |
−0.6 (−1.1, −0.1) 0.011 |
0.248 |
−1.9 (−2.9, −0.8) <.001 |
−1.5 (−2.6, −0.4) 0.019 |
0.580 |
−0.7 (−1.3, −0.1) 0.024 |
−1.8 (−2.5, −1.2) <.001 |
<.001 | −0.24 (−0.5, 0.4) 0.958 |
|
| Inferior |
−0.5 (−0.7, −0.2) 0.001 |
−0.3 (−0.6, 0.03) 0.076 |
0.501 |
−2.1 (−3.0, −1.2) <.001 |
−1.6 (−2.6, −0.7) 0.010 |
0.392 | −0.3 (−0.8, 0.2) 0.196 |
−1.8 (−2.3, −1.2) <.001 |
<.001 | −0.38 (−0.6, 0.2) 0.170 |
|
| Nasal | −0.06 (−0.7, 0.2) 0.862 |
−0.5 (−1.3, 0.3) 0.200 |
0.379 | −1.5 (−3.3, 0.4) 0.118 |
−1.3 (−3.2, 0.6) 0.138 |
0.882 | −0.4 (−1.5, 0.6) 0.399 |
−1.7 (−2.8, −0.6) 0.002 |
0.024 | −0.41 (−0.7, 0.2) 0.460 |
|
| Temporal |
−0.9 (−1.7, −0.2) 0.041 |
−0.1 (−1.2, 0.9) 0.806 |
0.271 |
−2.8 (−4.8, −0.8) 0.007 |
−1.4 (−3.5, −0.8) 0.149 |
0.261 | −0.3 (−1.5, 0.9) 0.654 |
−1.2 (−2.6, −0.1) 0.076 |
0.168 | −0.43 (−0.8, 0.8) 0.723 |
|
|
% Rim Area Change from baseline (%/year) |
Global | −0.2 (−0.3, 0.1) 0.174 |
−0.2 (−0.4, 0.03) 0.098 |
0.678 |
−1.2 (−1.9, −0.6) <.001 |
−1.1 (−1.8, −0.4) 0.013 |
0.697 | −0.2 (−0.5, 0.1) 0.196 |
−1.1 (−1.5, −0.8) <.001 |
<.001 | −0.08 (−0.2, 0.1) 0.290 |
| Superior | −0.1 (−0.3, 0.2) 0.554 |
−0.3 (−0.6, −0.02) 0.039 |
0.223 |
−1.5 (−2.3, −0.7) <.001 |
−1.2 (−2.0, −0.3) 0.018 |
0.509 | −0.4 (−0.7, 0.0) 0.050 |
−1.3 (−1.8, −0.9) <.001 |
<.001 | 0.03 (−0.2, 0.4) 0.573 |
|
| Inferior |
−0.2 (−0.3, −0.1) 0.009 |
−0.2 (−0.4, 0.0) 0.056 |
0.845 |
−1.7 (−2.5, −0.8) <.001 |
−1.5 (−2.3, −0.6) 0.009 |
0.723 | −0.2 (−0.5, 0.2) 0.268 |
−1.5 (−1.9, −1.1) <.001 |
<.001 | −0.11 (−0.3, 0.1) 0.170 |
|
| Nasal | 0.04 (−0.1, 0.2) 0.612 |
−0.1 (−0.3, 0.1) 0.237 |
0.215 | −0.5 (−1.4, 0.4) 0.245 |
−0.7 (−1.6, 0.2) 0.089 |
0.694 | −0.2 (−0.6, 0.3) 0.441 |
−0.7 (−1.2, −0.2) 0.003 |
0.023 | −0.03 (−0.1, 0.1) 0.183 |
|
| Temporal | −0.2 (−0.7, 0.3) 0.460 |
0.1 (−0.5, 0.7) 0.685 |
0.432 |
−2.0 (−3.3, −0.8) 0.001 |
−1.1 (−2.4, 0.2) 0.077 |
0.213 | −0.01 (−0.7, 0.7) 0.974 |
−1.16 (−1.2, −0.4) 0.005 |
0.004 | −0.1 (−0.2, 0.2) 0.390 |
|
Abbreviations: HRT, Heidelberg Retina Tomograph; CI, Confidence Interval