Table 3.
Anti-HIV Data of the Isolates from E. sikkimensis
| compound | EC50 (μM) | number of tests | CC50 (μM) | SI (CC50/EC50)b |
|---|---|---|---|---|
| 1a | 6.3 ± 2.1 | 3 | 21 ± 1.1 | 3.3 |
| 1b | 5.3 ± 1.2 | 3 | 17 ± 1.2 | 3.2 |
| 2a a | >10 | 1 | >10 | |
| 2b a | >10 | 1 | >10 | |
| 5 a | >10 | 1 | >10 | |
| 8 a | >10 | 1 | >10 | |
| 9 a | >10 | 1 | >10 | |
| AZT | 0.004 ± 0.0012 | 3 | >0.1 | >25 |
a
The highest concentration tested was 10 μM for all the samples in the first test; 0.1 μg/mL for the control AZT. Testing concentration ranges were adjusted in subsequent tests based on potency.
b
SI is the selective index, SI = CC50/EC50.