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. Author manuscript; available in PMC: 2017 Apr 1.

Published in final edited form as: Neurogastroenterol Motil. 2015 Dec 20;28(4):513–521. doi: 10.1111/nmo.12745

Symptom burden measured as GSS at baseline and follow up were significantly different across GERD phenotypes. RH=reflux hypersensitivity. A. Off PPI. Baseline and follow up global symptom severity (GSS) on 100-mm visual analog scales was lowest with equivocal or no GERD evidence, and followed a gradient along increasing strength of GERD evidence. These differences were statistically significant across groups. B. On PPI. While baseline and follow up GSS were not significantly different, the change in GSS followed the same gradient along increasing strength of GERD evidence, and trended strongly towards statistical significance.

Symptom burden measured as GSS at baseline and follow up were significantly different across GERD phenotypes. RH=reflux hypersensitivity. A. Off PPI. Baseline and follow up global symptom severity (GSS) on 100-mm visual analog scales was lowest with equivocal or no GERD evidence, and followed a gradient along increasing strength of GERD evidence. These differences were statistically significant across groups. B. On PPI. While baseline and follow up GSS were not significantly different, the change in GSS followed the same gradient along increasing strength of GERD evidence, and trended strongly towards statistical significance.