Figure 6. There is a significant decrease in the hypoxyprobe index in LV-shRNA-Vegf-A transduced vessels when compared to controls.
Pooled data for the LV-shRNA-Vegf-A and control shRNA groups each at day 21, 28, and 42 is shown. This demonstrates a significant reduction in the average hypoxyprobe index in the LV-shRNA-Vegf-A transduced vessels when compared to controls at day 21 after first administration. Two-way ANOVA followed by Student t-test with post hoc Bonferroni’s correction was performed. Significant difference from control value was indicated by ##P<0.0001. Each bar shows mean ± SEM of 4–6 animals per group.