Skip to main content
. 2016 Mar 13;2016:7841718. doi: 10.1155/2016/7841718

Table 2.

Th17 cells, serum IL-17, and IL-23 levels with respect to disease activity parameters and immunosuppressants.

Activity measured by NIH criteria
Active (n = 13) Inactive (n = 17) p value (Mann-Whitney)
Th17 cells (%) 2.1 (1.4–3) 2.05 (1.6–4.3) (n = 16) 0.55
IL-17A (pg/mL) 7.4 (4.7–9) 5.3 (4.4–8.5) 0.56
IL-23 (pg/mL) 14.9 (14.9–17.7) 15 (14.9–30.5) 0.07

Activity measured by ITAS2010 ≥ 4
Active (n = 12) Inactive (n = 18) p value (Mann-Whitney)

Th17 cells (%) 2.2 (1.4–3.1) 1.9 (1.6–4.2) (n = 17) 0.80
IL-17A (pg/mL) 7.7 (4.7–9.2) 5.4 (4.4–8.6) 0.54
IL-23 (pg/mL) 14.9 (14.9–19) 15 (14.9–28.7) 0.13

Data with respect to immunosuppressants
Not on immunosuppressants (n = 13) On immunosuppressants∗∗ (n = 17) p value (Mann-Whitney)

Th17 cells (%) 2 (1.3–2.8) 2.3 (1.6–3.8) (n = 16) 0.30
IL-17A (pg/mL) 6.5 (4.7–9) 6.1 (4.4–8.6) 0.85
IL-23 (pg/mL) 14.9 (14.9–20.6) 15 (14.9–26.6) 0.36

Values represented as median with interquartile range in brackets.

Th17 cell population could not be studied in one patient due to technical difficulties.

∗∗14 patients were on prednisolone, 11 on oral methotrexate, and 3 on azathioprine.