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Numbers of misidentified CpG sites versus cutoff frequency for a CpG site being potentially important (based on ordinary least squares regressions). The true numbers of important CpG sites are (a) 10, (b) 100, (c) 200, and (d) 400 out of 2,000 CpG sites across 800 subjects. For the TT screening method, significance levels considered are 0.05 for both training and testing data. For the FDR-based and Bonferroni methods, the level was set at 0.05.
