Table 7.
Information for CpG sites associated with maternal smoking identified by the training and testing screening method.
| Model 2: maternal smoking only | ||||
|---|---|---|---|---|
| CpG site | Chromosome: map | Gene | Promoter region | CpG island |
| name | information | name | and exon | location |
| cg20464068 | chr1: 14026054 | PRDM2 | TSS1500 | 14026481–14027200 |
| cg07951355 | chr1: 40123717 | |||
| cg14179389 | chr1: 92947961 | GFI1 | Body | 92945907–92952609 |
| cg00909806 | chr1: 212688762 | 212688031–212688448 | ||
| cg26143053 | chr2: 3718125 | ALLC | 5′UTR | |
| cg03690080 | chr2: 39188006 | LOC100271715, LOC375196 | Body, TSS1500 | 39186777–39187968 |
| cg19243656 | chr2: 73340094 | RAB11FIP5 | 5′UTR, 1stExon | 73339292–73340733 |
| cg18703066‡ | chr2: 105363536 | |||
| cg07516970 | chr2: 157181359 | NR4A2 | 3′UTR | 157184389–157184632 |
| cg19273101 | chr2: 191734576 | |||
| cg14075934 | chr2: 200137014 | SATB2 | Body | |
| cg03158780 | chr3: 577964 | |||
| cg10663973 | chr4: 6642559 | MRFAP1 | 1stExon, 5′UTR | 6642194–6643322 |
| cg10364374 | chr4: 125857940 | |||
| cg23743778 | chr4: 140357491 | 140357362–140357610 | ||
| cg21401642 | chr4: 174421114 | 174421347–174421559 | ||
| cg17924476† | chr5: 323794 | AHRR | Body | 320788–323010 |
| cg05575921 | chr5: 373378 | AHRR | Body | 373842–374426 |
| cg21161138 | chr5: 399360 | AHRR | Body | |
| cg12287936 | chr5: 1800606 | NDUFS6, MRPL36 | TSS1500 | 1799461–1801905 |
| cg16244648 | chr5: 141555043 | |||
| cg18349863 | chr6: 29912713 | HLA-A | Body | 29910202–29911367 |
| cg11492288 | chr6: 30290596 | HCG18 | Body | 30294169–30295071 |
| cg04325960 | chr6: 147124986 | LOC729176, C6orf103 | TSS200, Body | |
| cg00004963 | chr6: 147124996 | LOC729176, C6orf103 | TSS200, Body | |
| cg11881038 | chr6: 154408701 | OPRM1 | Body, 1stExon, 5′UTR | |
| cg20418529 | chr6: 166260012 | |||
| cg00794911 | chr6: 166260532 | |||
| cg18132363† | chr6: 166260572 | |||
| cg08634229 | chr6: 169326603 | |||
| cg06769202 | chr7: 27142535 | HOXA2 | TSS200 | 27143181–27143479 |
| cg23206851 | chr7: 27143046 | HOXA2 | TSS1500 | 27143181–27143479 |
| cg02225599 | chr7: 27143252 | HOXA2 | TSS1500 | 27143181–27143479 |
| cg10319053 | chr7: 27143370 | HOXA2 | TSS1500 | 27143181–27143479 |
| cg00445443 | chr7: 27143478 | HOXA2 | TSS1500 | 27143181–27143479 |
| cg06401979 | chr7: 27143717 | HOXA2 | TSS1500 | 27143181–27143479 |
| cg11986226 | chr7: 40026390 | CDK13 | Body | |
| cg19089201‡ | chr7: 45002287 | MYO1G | 3′UTR | 45002111–45002845 |
| cg04180046‡ | chr7: 45002736 | MYO1G | Body | 45002111–45002845 |
| cg12803068‡ | chr7: 45002919 | MYO1G | Body | 45002111–45002845 |
| cg25949550‡ | chr7: 145814306 | CNTNAP2 | Body | 145813030–145814084 |
| cg11207515 | chr7: 146904205 | CNTNAP2 | Body | |
| cg21015808 | chr7: 149809179 | |||
| cg21330896 | chr7: 28205705 | ZNF395 | 3′UTR | |
| cg17199018 | chr7: 28206278 | ZNF395 | Body | |
| cg04690729 | chr8: 133494328 | KCNQ3 | TSS1500 | 133492398–133493586 |
| cg15707110 | chr8: 144311102 | 144311708–144311985 | ||
| cg08126560 | chr9: 92291523 | LOC100129066 | Body | 92291268–92291524 |
| cg13393408 | chr9: 132874232 | GPR107 | Body | |
| cg11813497 | chr10: 14372879 | FRMD4A | TSS200 | |
| cg12490835 | chr10: 22623821 | 22623350–22625875 | ||
| cg26520012 | chr10: 42672589 | 42672509–42673432 | ||
| cg05329352 | chr10: 112838983 | ADRA2A | 1stExon | 112835990–112839303 |
| cg18424850 | chr10: 132945786 | TCERG1L | Body | |
| cg19494188 | chr11: 1466780 | BRSK2 | Body | 1466304–1467210 |
| cg26204383 | chr11: 2435667 | TRPM5 | Body | 2435295–2436651 |
| cg14436038 | chr11: 6494706 | TRIM3 | 5′UTR | 6494725–6495453 |
| cg15627089 | chr11: 16625751 | 16626053–16629180 | ||
| cg25160605 | chr11: 21087846 | NELL1 | Body | |
| cg17517598 | chr11: 61659090 | FADS3 | TSS200 | 61658569–61659592 |
| cg10788371 | chr11: 76381040 | LRRC32 | 5′UTR, 1stExon | 76381449–76382295 |
| cg11395306 | chr11: 98939366 | CNTN5 | 5′UTR | |
| cg01186919 | chr11: 111742365 | ALG9 | TSS1500, TSS200 | 111741953–111742292 |
| cg02820646 | chr11: 115398838 | |||
| cg05730269 | chr11: 118477055 | PHLDB1 | TSS200, TSS1500 | 118478235–118481896 |
| cg18493761 | chr11: 125386885 | |||
| cg09932758 | chr12: 58022542 | B4GALNT1 | Body | 58021294–58022037 |
| cg09644707 | chr12: 114885161 | 114885105–114885418 | ||
| cg27103591 | chr12: 124809023 | NCOR2 | 3′UTR | 124808972–124809176 |
| cg02032696 | chr14: 67982198 | TMEM229B | TSS200 | 67981514–67982380 |
| cg21511816 | chr14: 76597824 | 76597648–76597911 | ||
| cg24874277 | chr15: 33211107 | FMN1 | Body | |
| cg03643241 | chr15: 44487910 | FRMD5 | TSS1500 | 44486741–44487860 |
| cg20596162 | chr15: 45408861 | DUOXA2 | Body | 45408573–45409528 |
| cg16754378 | chr15: 57179394 | LOC145783 | Body | 57179277–57179838 |
| cg06899985 | chr15: 65689298 | IGDCC4 | Body | 65689142–65689362 |
| cg05549655† | chr15: 75019143 | CYP1A1 | TSS1500 | 75018186–75019336 |
| cg17852385 | chr15: 75019188 | CYP1A1 | TSS1500 | 75018186–75019336 |
| cg11924019† | chr15: 75019283 | CYP1A1 | TSS1500 | 75018186–75019336 |
| cg18092474† | chr15: 75019302 | CYP1A1 | TSS1500 | 75018186–75019336 |
| cg01060282 | chr16: 17033575 | |||
| cg07675285 | chr16: 27121267 | 27121011–27121241 | ||
| cg11705699 | chr16: 87742845 | KLHDC4 | Body | 87742556–87743109 |
| cg09554007 | chr16: 89627174 | RPL13, SNORD68 | 5′UTR, 1stExon, TSS1500 | 89626644–89627869 |
| cg16483033 | chr17: 1090441 | ABR | 1stExon, 5′UTR | |
| cg08682866 | chr17: 13818946 | |||
| cg17624073 | chr17: 79393583 | BAHCC1 | Body | 79393341–79393742 |
| cg13723693 | chr17: 80656731 | RAB40B | TSS200 | 80655335–80657183 |
| cg18495341 | chr17: 80909836 | B3GNTL1 | Body | |
| cg18449879 | chr19: 16045054 | CYP4F11 | 1stExon, Body | |
| cg02543506 | chr20: 33876594 | FAM83C | Body | 33879904–33880215 |
CpG: cytosine-phosphate-guanine dinucleotide, chr: chromosome, locations of each CpG are for v37 of the human genome, †CpG sites identified by false discovery rate, and ‡CpG sites identified by false discovery rate and Bonferroni-based methods.