Table 2.
Significant Clusters Observed in the Posterior Cingulate Cortex (PCC) Seed-Based Connectivity Analysis
| Contrast | Region | BA | Network | x | y | z | Peak T | # Voxels |
|---|---|---|---|---|---|---|---|---|
| Healthy > PTSD Youth | Right IFG | 6, 22 | TPN | −66 | 6 | 6 | −4.55 | 300 |
| dACC / pre-SMA | 6, 24 | TPN | −2 | 6 | 60 | −4.32 | 282 | |
| Right IPS | 40 | TPN | −60 | 26 | 32 | −3.76 | 200 | |
| PTSD > Healthy Youth | Left IPG | 40 | DMN | 46 | 56 | 54 | 4.55 | 188 |
| Group × Age: PTSD > Healthy Youth | MFG | 11 | DMN | 6 | −62 | −14 | 4.67 | 163 |
| Cerebellum | -- | -- | −26 | 70 | −30 | 3.92 | 205 | |
Note: The peak coordinates are in Montreal Neurological Institute (MNI) space (RAI orientation). Peak T statistics are derived from the contrast posttraumatic stress disorder (PTSD) – Healthy.
BA = Brodmann Area; dACC = dorsal anterior cingulate cortex; DMN = default-mode network; IPG = inferior parietal gyrus; IPS = inferior parietal sulcus; Pre-SMA = pre-supplementary motor area; TPN = task-positive network; vmPFC = ventromedial prefrontal cortex.