Table 4.
The distribution of subgroup classification among the N=488 patients with identified disease etiologies (non-IND) and sufficient data on INR, total bilirubin and HE, overall and by disease etiology. Each row represents the distribution of subgroup classifications within a specific diagnostic category. The distribution of subgroups are significantly different across different diagnostic categories (p<.001).
| categories | N | Subgroup1 | Subgroup2 | Subgroup3 | Subgroup4 | Subgroup5 |
|---|---|---|---|---|---|---|
| All non-IND | 488 | 136(28%) | 95(19%) | 61(13%) | 135(28%) | 61(13%) |
| Diagnosis | ||||||
| Acetaminophen | 107 | 71(66%) | 20(19%) | 11(10%) | 2(2%) | 3(3%) |
| Drug-induced hepatitis | 21 | 5(24%) | 7(33%) | 2(10%) | 6(29%) | 1(5%) |
| Hemophagocytic Syndrome | 22 | 1(5%) | 5(23%) | 4(18%) | 4(18%) | 8(36%) |
| Hepatitis, A/B/C/E | 11 | 1(9%) | 7(64%) | 1(9%) | 2(18%) | 0(0%) |
| Other viral hepatitis | 54 | 11(20%) | 4(7%) | 3(6%) | 26(48%) | 10(19%) |
| Shock/ischemia | 31 | 12(39%) | 6(19%) | 7(23%) | 2(6%) | 4(13%) |
| Neonatal iron storage | 26 | 1(4%) | 2(8%) | 1(4%) | 15(58%) | 7(27%) |
| Veno-oclusive disease | 12 | 0(0%) | 3(25%) | 2(17%) | 7(58%) | 0(0%) |
| Wilsons disease | 31 | 0(0%) | 9(29%) | 6(19%) | 12(39%) | 4(13%) |
| Other Metabolic | 58 | 11(19%) | 14(24%) | 14(24%) | 15(26%) | 4(7%) |
| Autioimmune Hepatitis | 63 | 5(8%) | 12(19%) | 7(11%) | 30(48%) | 9(14%) |
| Other diagnosis | 31 | 11(35%) | 3(10%) | 2(6%) | 9(29%) | 6(19%) |
| Multiple | 21 | 7(33%) | 3(14%) | 1(5%) | 5(24%) | 5(24%) |