Table 1.

Cox Proportional Hazards Regression Analyses for Associations with Disease-Specific Survival

Covariate*	Univariable hazard ratio (95% CI)	p Value†	Multivariable‡ hazard ratio (95% CI)	p Value
Subtypes	3.64 (1.53–8.70)	0.004	3.53 (1.41–8.85)	0.007
Grade	6.24 (2.56–15.23)	<0.001	6.84 (2.57–18.17)	<0.001
R	2.51 (1.54–4.08)	<0.001	—	—
ECOG	2.91 (1.71–4.95)	<0.001	2.07 (1.22–3.52)	0.007
Age	0.99 (0.96–1.03)	0.63	—	—

^*Subtypes and grade were entered as binary variables; R (Surgical Score) and ECOG status were entered as semi-continuous variables (R = 1, 2, 3; ECOG = 0, 1, 2, 3); age was entered as a continuous variable.

^†Wald p value.

^‡Stepwise selection procedure with entry significance level 0.05.

ECOG, Eastern Cooperative Oncology Group.