Table 2.

Cox Proportional Hazards Regression Analyses for Associations with Progression-Free Survival

Covariate*	Univariable hazard ratio (95% CI)	p Value†	Multivariable‡ hazard ratio (95% CI)	p Value
Subtypes	3.16 (1.64–6.10)	<0.001	3.27 (1.58–6.75)	0.001
Grade	3.52 (1.71–7.23)	<0.001	3.32 (1.57–7.01)	0.002
R	2.03 (1.38–2.98)	<0.001	1.56 (1.04–2.35)	0.03
ECOG	1.77 (1.13–2.80)	0.01	—	—
Age	1.00 (0.97–1.02)	0.8	—	—

^*Subtypes and grade were entered as binary variables; R (Surgical Score) and ECOG status were entered as semi-continuous variables (R = 1, 2, 3; ECOG = 0, 1, 2, 3); age was entered as a continuous variable.

^†Wald p value.

^‡Stepwise selection procedure with entry significance level 0.05.

ECOG, Eastern Cooperative Oncology Group.