Table 2.
Comparison of serum and tissue oxidant and antioxidant parameters.
Parameters | Group 1 | Group 2 | Group 3 | Group 4 |
---|---|---|---|---|
(n = 7) | (n = 7) | (n = 7) | (n = 7) | |
Serum | ||||
MDA (mmol/mL) | 0.73 ± 0.17 | 1.67 ± 0.32d | 1.28 ± 0.21b | 0.90 ± 0.26c,e |
TOS (μmol/L) | 33.59 ± 11.23 | 80.30 ± 11.26d | 52.73 ± 12.48c | 39.07 ± 7.07c,e |
NO (μM/L) | 4.85 ± 0.39 | 5.80 ± 0.46a | 5.41 ± 0.32c | 4.90 ± 0.32b,c |
TNF-α (pg/mL) | 2.72 ± 1.45 | 18.50 ± 10.01a | 9.01 ± 2.06b | 5.77 ± 2.34b,c |
TAC (mmol/L) | 1.32 ± 0.10 | 0.87 ± 0.30a | 1.18 ± 0.10b | 1.56 ± 0.11e,f |
PON (U/L) | 197.03 ± 37.63 | 124.61 ± 15.81a | 145.67 ± 7.75b | 157.70 ± 10.25b,c |
Peritoneal tissue | ||||
MDA (mmol/mL) | 0.12 ± 0.25 | 1.31 ± 0.41d | 0.59 ± 0.35b | 0.12 ± 0.07c,e |
TOS (μmol/L) | 7.16 ± 3.53 | 45.90 ± 26.57a | 14.18 ± 4.58b | 8.77 ± 4.11b,c |
NO (μM/L) | 3.95 ± 0.87 | 6.65 ± 1.36a | 6.00 ± 0.52 | 5.29 ± 0.22b,c |
TNF-α (pg/mL) | 116.39 ± 42.36 | 487.21 ± 238.44a | 265.22 ± 52.74b | 136.83 ± 24.26b,f |
TAC (mmol/L) | 0.80 ± 0.11 | 0.34 ± 0.08d | 0.47 ± 0.064b | 0.66 ± 0.14c,e |
PON (U/L) | 12.74 ± 3.32 | 1.83 ± 2.54d | 4.82 ± 1.37b | 8.34 ± 1.14e,f |
MDA: malondialdehyde, NO: nitric oxide, TNF-α: tumor necrosis factor alpha, TAC: total antioxidant capacity, TOS: total oxidant stress, and PON: paraoxonase.
a p < 0.005 as compared to group 1, b p < 0.005 as compared to group 2, c p < 0.005 as compared to group 3, d p < 0.001 as compared to group 1, e p < 0.001 as compared to group 2, and f p < 0.001 as compared to group 3.