Table I.

Five diagnostic criteria for SDRIFE

Occurrence after exposure to systemic drug at first or on repeated doses Sharply demarcated erythema of buttocks or V-shaped erythema of thighs Involvement of at least one other flexural fold Symmetry of affected areas Absence of systemic symptoms and signs

Adapted with permission from Hausermann P, Harr T, Bircher AJ. Baboon syndrome resulting from systemic drugs: is there strife between SDRIFE and allergic contact dermatitis syndrome? Contact Dermatitis. 2004; 51(5-6):297-310.