Table 3:

Factors Informing Patient Risk Stratification in Pediatric Patients with De Novo Acute Lymphoblastic Leukemia

Risk Group	Age, Years	White Blood Cell Count at Diagnosis	Other Influential Factors
Standarda risk	1 to < 10	< 50 000/µL	T-cell or B-cell origin (immunophenotype) Chromosomal changes in lymphocyte genes (cytogenetics)
High risk	≥ 10	≥ 50 000/µL	Rapidity and magnitude of drop in leukemic cell count after induction therapy Presence of leukemic cells in cerebrospinal fluid

^aMay also be referred to as low risk.

Source: National Cancer Institute.³