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Mutation frequency of fpg mutY strains expressing bacterial and human DNA repair genes
| Strain | Genotype | Plasmid | Mutation frequency (mutants/108 cells)a |
|---|---|---|---|
| MV4724 | Wild type | pTrc99A vector | 3 |
| MV4755 | fpg mutY | pTrc99A vector | 2,750 |
| MV4763 | fpg mutY | pTrc99A-fpg | 0 |
| MV4761 | fpg mutY | pTrc99A-hOGG1 | 11 |
| MV4762 | fpg mutY | pTrc99A-hMYH | 58 |
| MV4722 | fpg mutY | pSE380b-PC4 | 0 |
Representative data are shown.
pSE380 is identical to pTrc99A except for the presence of additional cloning sites in the vector.
