. 2016 Mar 11;8(3):161. doi: 10.3390/nu8030161

Table 3.

Insulin secretion capacity during hyperglycemic clamp.

	Control (n = 8)	GEB-L (n = 8)	GEB-H (n = 8)	Positive-Control (n = 8)
Overnight fasted serum glucose (mg/dL)	132 ± 16 ^a	120 ± 17 ^a,b	108 ± 14 ^b	106 ± 11 ^c
Overnight fasted serum insulin (ng/mL)	0.97 ± 0.11	0.99 ± 0.14	1.05 ± 0.12	1.04 ± 0.11
Area under the curve of serum insulin at first phase (ng/mL·min)	20.7 ± 2.1 ^c	24.7 ± 3.0 ^b	29.4 ± 3.1 ^a	20.5 ± 2.7 ^c
Area under the curve of serum insulin at second phase (ng/mL·min)	258 ± 28 ^b	254 ± 27 ^b	291 ± 30 ^a	240 ± 27 ^b
Glucose infusion rate (mg/kg bw/min)	8.3 ± 1.0 ^c	10.6 ± 1.2 ^b	13.4 ± 1.5 ^a	12.7 ± 1.5 ^a
Insulin sensitivity (µmol glucose·min⁻¹·100 g⁻¹ per µmol insulin/L)	12.5 ± 1.4 ^d	14.6 ± 1.6 ^c	16.4 ± 1.7 ^b	18.3 ± 1.7 ^a

Values are means ± standard deviation. Px rats were fed a high-fat diet supplemented with (1) 0.5% water extract of Gastrodia elata Blume (GEB-L), (2) 2% water extract of Gastrodia elata Blume (GEB-H), (3) 2% dextrin (Px-control), or (4) rosiglitazone (20 mg/kg body weight; positive control) for eight weeks. ^a,b,c Means on the same row with different superscripts were significantly different at p < 0.05.