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. 2016 Mar 24;6(3):e010360. doi: 10.1136/bmjopen-2015-010360

Table 4.

Changes in intraocular pressure with ageing and changes in metabolic syndrome parameters: 10-year longitudinal study (n=15 747)

Univariate analyses
Multivariate analysis
Explanatory variable Coefficient 95% CI p Value Coefficient 95% CI p Value
Sex, men −0.35 −0.39 to −0.32 <0.0001 −0.12 −0.16 to −0.08 <0.0001
Ageing, +10 years −0.73 −0.77 to −0.69 <0.0001 −0.59 −0.64 to −0.54 <0.0001
HDL-C, +1 mmol/L +0.28 0.21 to 0.35 <0.0001 +0.42 0.35 to 0.49 <0.0001
(HDL-C, +10 mg/dL) +0.073 0.055 to 0.090 <0.0001 +0.11 0.09 to 0.13 <0.0001
Triglyceride, +1 mmol/L +0.095 0.077 to 0.11 <0.0001 +0.092 0.073 to 0.11 <0.0001
(Triglyceride, +10 mg/dL) +0.011 0.0086 to 0.013 <0.0001 +0.010 0.008 to 0.012 <0.0001
SBP, +10 mm Hg +0.16 0.15 to 0.17 <0.0001 +0.090 0.077 to 0.10 <0.0001
DBP, +10 mm Hg +0.20 0.19 to 0.22 <0.0001 +0.085 0.067 to 0.10 <0.0001
FPG, +1 mmol/L +0.042 0.021 to 0.063 <0.0001 +0.091 0.071 to 0.11 <0.0001
(FPG, +10 mg/dL) +0.023 0.012 to 0.035 <0.0001 +0.051 0.039 to 0.062 <0.0001

DBP, diastolic blood pressure; FPG, fasting plasma glucose; HDL-C, high-density lipoprotein cholesterol; SBP, systolic blood pressure.