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. 2016 Mar 22;6(3):e010119. doi: 10.1136/bmjopen-2015-010119

Table 1.

HRAs considered for each condition, with frequencies

  Pharmacological treatment
Supervised intervention
Unsupervised behavioural intervention
Monitoring and follow-up
HRA Frequency HRA Frequency HRA Frequency HRA Frequency
Hypertension Thiazide-type diuretics
ACE inhibitors* (plus calcium-channel antagonist†)
1/day
1/day
Multidisciplinary team (educator, dietician) 1/year Diet (Dietary Approaches to Stop Hypertension (DASH) diet)
Physical activity
Daily
3/week
Blood test
12-lead electrocardiography
Physician appointment
Home blood pressure monitoring‡
1/year
1/year
1/year
1/day
Diabetes Statin
Metformine
ACE inhibitors* (plus calcium-channel antagonist†)
Influenza vaccine
Pneumococcal vaccine
1/day
3/day
1/day
1/year
1/5 years
Counselling with qualified professional
Self-management
1/year
1/year
Diet
Physical activity
Daily
2/week
Self-monitoring blood glucose
Blood and urine tests
Physician appointment
Ophthalmologist
2/years
1/year
1/year
1/year
CHD+tobacco consumption β-blockers
Aspirin
Statin
ACE inhibitors*
Nicotine substitute
Influenza vaccine
1/day
1/day
1/day
1/day
2/day
1/year
Individualised education
Stop smoking: intensive counselling
1/year
4/month
Diet
Physical activity
Daily
1/day
Blood test
12-lead-electrocardiography
Physician appointment
Radionuclide myocardial perfusion imaging or echocardiography
or cardiac MRI
1/year
1/year
1/year
1/2 years
COPD+tobacco consumption Combination of long-acting bronchodilatators and inhaled corticosteroids
Nicotine substitute
Influenza vaccine
Pneumococcal vaccine
2/day
2/day
1/year
1/5 years
Stop smoking: intensive counselling 4/month Physical activity 1/day Spirometry
Physician appointment
1/year
1/year
Depression Selective serotonin reuptake inhibitors 1/day Physical activity 3/week Health caregiver (collaborative care approach) 1/month
Knee osteorthritis+overweight Acetaminophen or NSAIDs (included COX-2) or tramadol
Topical NSAIDs
Intra-articular corticosteroid injections
3/day
2/day
3/year
Education 1/year Cardiovascular aerobic and/or resistance land-based exercise
Diet
Use of thermal agents
Walking aids
5/week
daily
Physician appointment 1/year
Prevention services Influenza 1/year Occult blood testing or colonoscopy or sigmoidoscopy 1/5 year

*Use ACE inhibitors when CHD is associated with hypertension (instead of thiazide-type diuretics) or diabetes.

†Use ACE inhibitors and calcium-channel antagonist if hypertension is associated with diabetes.

‡Home blood pressure monitoring when hypertension is associated with diabetes.CHD, coronary heart disease; COPD, chronic obstructive pulmonary disease; COX-2, cyclooxygenase 2; HRAs, health-related activities; NSAIDs, non-steroidal anti-inflammatory drugs.