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. 2016 Apr;89(4):399–406. doi: 10.1124/mol.115.102202

Fig. 1.

Fig. 1.

Structures of steroids and analogs tested in the study. Enantiomeric steroids (e18,19dinor3α5α16O, e18nor3α5α16O, e3α5β17O, e3α5α4βOMe16O, e19nor3α5α16O, and e3α5α16) are inverted relative to natural steroids when bound to GABAA receptors. For models of the modes of binding natural steroids and their enantiomers, see (Krishnan et al., 2012; Qian et al., 2014).