TABLE 1.
Receptor binding data for 5-HT2 receptor ligands
| Drug Name | 5-HT2A | 5-HT2B | 5-HT2C |
|---|---|---|---|
| DOI | 7.4–9.2 | 7.6 – 7.7 | 7.2–8.6 |
| CP-809,101 | 6.8 | 7.2 | 10.0 |
| SB-242,084 | 6.1–6.8 | 6.8–7.0 | 8.2–9.0 |
| Eplivanserin | 9.4 | — | 6.13 |
| NBOH-2C-CN | 8.9 | — | 6.9 |
pKi values for DOI and SB-242,084 are reported by the IUPHAR Database. pEC50 values for CP-809,101 are reported by Siuciak et al. (2007). Whole-cell pKi values for eplivanserin are reported by Vanover and Davis (2010). Whole-cell pKi values for NBOH-2C-CN are reported by Hansen et al. (2014).