TABLE 2.

Summary of in vitro COX inhibition assays

IC₅₀ values reflect the mean ± standard error of the mean from three experiments (n = 2 replicates per experiment).

Compound	COX-1 IC50	COX-2 IC50
	μM	μM
SC-560 (COX-1 selective)	0.00166 ± 0.00022	N.D.
DuP-697 (COX-2 selective)	N.D.	0.00714 ± 0.0007
DCF	0.0206 ± 0.0037	0.103 ± 0.005
OH-DCF	0.375 ± 0.075	21.2 ± 0.3
DCF-AG	0.620 ± 0.105	2.91 ± 0.36

N.D., not determined.