Fig. 1.

DIM treatment reduces SEB-induced inflammation and capillary leak in the lungs. (A) H&E staining of lung sections from different treatment groups. The photographs were taken at 40× magnification. (B) Quantification of the histopathology data. Layers of infiltrating cells were counted around 15 different capillaries of the same size, and the data represent the mean ± S.E.M. for each individual group. (C) Measurement of capillary leak in the lungs using Evans blue dye extravasation. Percent increase in vascular leak was calculated compared with control. Vertical bars represent data collected from four or five mice per group expressed as means ± S.E.M. Analysis of variance, ***P < 0.001; *P < 0.05 with Tukey’s test.