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. 2016 Mar 21;11:1131–1146. doi: 10.2147/IJN.S94467

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© 2016 Ju et al. This work is published and licensed by Dove Medical Press Limited

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Induction of apoptosis of brain glioma cells and mechanism after treatment with targeting epirubicin plus celecoxib liposomes.

Notes: (A) Induction of apoptosis in brain glioma. a, vs 1; b, vs 2; c, vs 3. (B) Expression changes of enzymes or proteins involved in apoptotic signaling pathways. The intensity of green fluorescence captured by the high content screening system indicates that the expressions of caspase-8, caspase-3, and Bax were enhanced, while the expression of Mcl-1 was decreased, after drug treatments. Images were obtained under a microscope at 80× magnification.