Table 2. Descriptive statistics and median group difference compared to controls for storytelling characteristics classified by diagnostic group (n=46).
bvFTD | svPPA | AD | NC | P value | |
---|---|---|---|---|---|
n=15 | n = 7 | n = 12 | n = 12 | ||
Conversational speech produced3 | |||||
Mean± s.d. | 126.8±78. | 241.6±187. | 167.1±123. | 133.3±54. | 0.31 |
Range | 5 | 9 | 8 | 9 | |
Median | 85-504 | 221-558 | 100-5.25 | 115-405 | |
284 | 366 | 354 | 288.5 | ||
Median group difference with controls (95% CI) | 11 (-87, 103) | 102.5 (-39, 226) | 59 (-51, 162) | ||
Social Attention | |||||
Mean± s.d. | 3±1.4 | 2.7±1.3 | 2.6±1.5 | 1.6±0.8 | 0.03 |
Range | 1-5.5 | 1-4.5 | 1-6 | 1-3 | |
Median | 2.5 a | 2.5 a | 2 | 1 | |
Median group difference with controls (95% CI) | -2.5 (-5,-1)** | 3 (0,4)* | -2 (-3,0) | ||
Story frequency | |||||
Mean± s.d. | 1.2±1.6 | 3.2±1.7 | 1.5±1.5 | 1.8±1.4 | 0.02 |
Range | 0-5 | 2-6 | 0-4 | 0-4 | |
Median | 1 | 3 | 1 | 2 | |
Median group difference with controls (95% CI) | 1(0, 2) | 1.5(0,3)* | 0(-1,2) | ||
| |||||
n = 8 | n = 7 | n = 8 | n = 9 | ||
| |||||
Story speech produced | |||||
Mean± s.d. | 126.8±78.5 | 241.6±187.9 | 167.1±123.8 | 133.3±54.9 | 0.65 |
Range | 27-230 | 50-558 | 33-316 | 15-193 | |
Median | 127.5 | 177 | 117 | 152 | |
Median group difference with controls (95% CI) | 3 (-103, 70) | 55 (-80, 307) | 18 (-97, 157) | ||
| |||||
bvFTD | svPPA | AD | NC | P value | |
n = 8 | n = 7 | n = 8 | n = 9 | ||
| |||||
Evaluation clauses | |||||
Mean ± s.d. | 1.1±0.5 | 2.2±1.8 | 1.9±1.1 | 1.2±0.6 | 0.16 |
Range | 0.6-2 | 0.7-5.5 | 1-3 | 0.5-2.33 | |
Median | 1 | 1.5 | 2.34 | 1 | |
Median group difference with controls (95% CI) | 0 (-0.7, 0.5) | 0.5 (0.3-3) | 0.7 (-0.3, 1.8) | ||
Action clauses | |||||
Mean± s.d. | 5.7±2.6 | 5.4±2.3 | 5.3±1.9 | 5.7±1.9 | 0.99 |
Range | 2-10.5 | 1.33-8 | 2-7.5 | 3-10 | |
Median | 5.5 | 5 | 5.38 | 5.33 | |
Median group difference with controls (95% CI) | 0.13 (-2.3, 2.2) | 0.3 (-2.8, 2.5) | -0.17 (-2.7, 2) | ||
Self-evaluation perseveration | |||||
Mean± s.d. | 1.5±0.8 | 4.1±3.7 | 2±0.7 | 1.4±0.3 | 0.04 |
Range | 1-3.33 | 1-12 | 1.4-3.67 | 1-2 | |
Median | 1.14 | 3 | 1.84 | 1.4 | |
Median group difference with controls (95% CI) | -0.19 (-0.5, 0.2) | 1.6(0.5, 3.1)* | 0.37 (0, 0.9) | ||
Autobiographical stories | |||||
Mean± s.d. | 1.8±1.4 | 3.1±1.4 | 0.9±1 | 1.8±0.8 | 0.01 |
Range | 1-5 | 1-5 | 0-3 | 1-3 | |
Median | 1 | 3 | 1 | 2 | |
Median group difference with controls (95% CI) | 0(-1,1) | 1 (0, 3)* | -1 (-2, 0)* | ||
Event specific | 0.77 | ||||
Mean± s.d. | 1±1.9 | 0.7±0.5 | 1.3±1.2 | 1.5±1.1 | |
Range | 0-3 | 0-1 | 0-2 | 0-3 | |
Median | 0.5 | 1 | 0.5 | 1 | |
Median group difference with controls (95% CI) | -1 (-2, 0) | 0 (-1, 0) | -0.5 (-1, 0) | ||
Temporal Organization (Local) | |||||
Mean± s.d. | 3.16±0.4 | 3.65±0.3 | 2.9±1 | 3.16±0.6 | 0.19 |
| |||||
bvFTD | svPPA | AD | NC | P value | |
n = 8 | n = 1 | n = 8 | n = 9 | ||
| |||||
Range | 2.67-4 | 3.25-4 | 2-4 | 2-4.25 | |
Median | 3 | 3.67 | 2.63 | 3 | |
Median group difference with controls (95% CI) | -0.05 (-0.5, 4) | -0.5 (-0.0, 1) | 0(-1,1) | ||
Temporal Organization (Global) | |||||
Mean± s.d. | 4.3±0.42 | 4.6±0.40 | 4.1±0.9 | 4.8±0.3 | 0.16 |
Range | 3-5 | 3.5-5 | 2.5-5 | 4-5 | |
Median | 4.33 | 4.67 | 4.16 | 5 | |
Median group difference with controls (95% CI) | -0.63 (-1, 0) | 0 (-0.7, 0) | -0.67 (-1.3, 0) | ||
Complexity | 0.11 | ||||
Mean± s.d. | 2.8±0.8 | 3.2±1 | 4.5±1.8 | 3.2±0.8 | |
Range | 1.67-4 | 2-4.75 | 2-7 | 2-5 | |
Median | 3 | 3.5 | 4.13 | 3 | |
Median group difference with controls (95% CI) | -.3 (-1, 0.25) | 0(-1, 1) | 1 (0, 3) |
Group effects on storytelling variables were analyzed using SAS 9.4
The first four rows represent the entire sample, the remaining six rows represent only the storytelling sample. NC = Normal Controls, AD = Alzheimer's dementia, bvFTD = behavioral variant frontotemporal dementia, svPPA = semantic variant primary progressive aphasia.
P values in the farthest right column are based on the Kruskal Wallis H test.
p<0.05 compared to Controls,
p<0.01 compared to Controls.