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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: J R Stat Soc Ser C Appl Stat. 2015 Oct 26;65(2):273–297. doi: 10.1111/rssc.12117

Table 1.

Toxicities and elicited severity weights for the 11 toxicities that are monitored in the esophageal cancer trial. Medical rationale to justify the numerical values is provided in Section A of the supplemental material.

Recurrent Toxicities Severity Level Elicited Weight

non-symptomatic 10
Pericardial Effusion (PEF) medical intervention 60
surgical intervention 90

non-symptomatic 10
Pleural Effusion (PLE) medical intervention 30
surgical intervention 60

grade 1-2 20
Radiation Pneumonitis (RP) grade 3 60
grade 4-5 90

Pneumonia (PNA) occurrence 40

Atrial Fibrillation (AFIB) occurrence 30

Myocardial Infarction (MI) occurrence 70

Postoperative Complications Severity Level Elicited Weight

radiographic only 30
Anastomotic Leak (AL) medical intervention 60
surgical intervention 90

Acute Respiratory Distress
Syndrome (ARDS)
occurrence 90

Pulmonary Embolism (PEM) occurrence 60

Reintubation (RI) occurrence 70

Stroke (ST) occurrence 90