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. Author manuscript; available in PMC: 2016 Aug 15.
Published in final edited form as: Clin Cancer Res. 2015 Oct 12;22(4):868–876. doi: 10.1158/1078-0432.CCR-15-0481

Figure 1.

Figure 1

RG7112 pharmacokinetics and pharmacodynamics data. A, Correlation between RG7112 dose (mg/day) and exposure (AUC2 24 h [ng/h/mL]) for Stratum A and Stratum B on day 10. The diamonds represent individual patients. B, Correlation between RG7112 levels in bone marrow (ng/mL) and plasma concentration (ng/mL). The diamonds represent individual patients. C, Correlation between mean serum MIC-1 levels (% change) and RG1172 plasma levels (AUC24 [μg/h/mL] on day 10. The diamonds represent individual patients. MIC-1, macrophage inhibitory cytokine-1; AUC, area under curve; D, day.