Skip to main content
. Author manuscript; available in PMC: 2016 Mar 28.
Published in final edited form as: Eur J Immunol. 2014 May 22;44(7):2036–2047. doi: 10.1002/eji.201444452

Figure 4. Patent filarial infection is associated with upregulation of activation-induced apoptotic genes.

Figure 4

(A) The death receptor-associated apoptosis pathways of the top 10% and two-fold differentially regulated genes in Treg cells from Fil+ subjects, relative to Treg cells from Fil− subjects are shown. Upregulated genes are shaded red while downregulated genes are shaded green. (B) The expression levels of apoptosis and/or survival genes in Treg cells from healthy donors (n= 15) left unstimulated (circle) or stimulated (square) with anti-CD3/CD28 beads are shown. Statistical significance determined by Wilcoxon matched-pairs signed rank test.