Table 1.
Characteristics of the cohort
| Characteristic | Patients (n = 130) |
|---|---|
| Age, years, median (IQR) | 60 (55–63) |
| Male sex | 95 (73.1) |
| Race/ethnicity | |
| White | 106 (81.5) |
| Black | 10 (7.7) |
| Other | 14 (10.8) |
| BMI, mean ± SD | 29.0 ± 5.31 |
| Past smoker | 95 (73.1) |
| Supplemental O2 at rest, L, median (IQR) | 3 (0–5) |
| Use of pulmonary vasodilators | 11 (8.5) |
| Pulmonary function test result | |
| FVC, L, mean ± SD | 2.2 ± 0.8 |
| FEV1, L, mean ± SD | 1.8 ± 0.6 |
| FEV1/FVC ratio, median (IQR) | 85.5 (81–90) |
| TLC, L, mean ± SD | 3.6 ± 0.9a |
| DLCO, mL/min/mmHg, median (IQR) | 9.3 (7.1–12.7)b |
| Six-minute walk test | |
| Total distance, m, mean ± SD | 379.1 ± 127.6 |
| Oxygen use during walk test | 104 (80.0) |
| Supplemental oxygen during walk test, L/min, median (IQR) | 6 (2–10) |
| Nadir oxygen saturation while receiving supplemental oxygen, %, mean ± SD | 88.3 ± 5.2 |
Note
Data are no. (%) of patients, unless otherwise indicated. BMI: body mass index, calculated as weight in kilograms divided by the square of height in meters; DLCO: diffusing capacity of the lung for carbon monoxide; FEV1: forced expiratory volume in 1 second; FVC: forced vital capacity; IQR: interquartile range; SD: standard deviation; TLC: total lung capacity.
a
n = 124.
b
n = 104.